Tokyo University of Science, Japan
Precise Synthesis and Application of Small Gold and Bi metal Clusters
Yuichi Negishi was born in Saitama, Japan, in 1972. He received his Ph.D. in chemistry in 2001 from Keio University. Before joining the Tokyo University of Science in 2008, he was employed at Keio University and at the Institute for Molecular Science (IMS). Since 2013, he has been an Associate Professor at the Tokyo University of Science. He is now the professor of Tokyo University of Science, Japan. He has over 150 publications that have been cited over 8,000 times. In his publications, 10 papers are/were categorized to Top 1% Cited Papers and 18 papers were selected as Cover Picture of the Journal. His publication H-index is 47. He has been awarded several prizes, including the PCCP Prize (2007), CSJ Award for Young Chemists (2008), Japan Society of Molecular Science Award for Young Chemists (2012), Yagami Prize (2017), and IUPAC Distinguish Award 2018 for Novel Materials and Their Synthesis (2018).
Thiolate (SR)-protected gold clusters (Aun(SR)m) show size-specific physical and chemical properties, such as photoluminescence, catalytic activity, and redox behavior, that are not observed in the case of bulk gold. Furthermore, it is possible to determine the geometrical structures of these clusters and therefore to elucidate correlations between their structures and physical properties. In addition, these clusters have been found to be highly stable both in solution and in the solid state. Owing to these numerous factors, Aun(SR)m clusters are considered to have significant potential as constituent units of functional nanomaterials. To date, our research group has studied the following three aspects of Aun(SR)m and related clusters: (1) the development of new methods allowing precise synthesis; (2) the establishment of new methods to impart high functionality; and (3) the utilization of these clusters as active sites in photocatalytic materials. This presentation summarizes our most recent work concerning these three subjects
University of Science and Technology Kraków (Poland), Poland
Application of the new numerical method to an analysis of carbon dioxide adsorption on NaY
Dr. Miroslaw Kwiatkowski in 2004 obtained Ph.D. degree from the Faculty of Energy and Fuels at the AGH University of Science and Technology in Kraków (Poland), and in 2018 D.Sc. degree from the Faculty of Chemistry at the Wroc?aw University of Technology (Poland) in the discipline: chemical technology. In addition, he obtained a certificate of completion of postgraduate studies: Professional Research and Development Project Manager at the Krakow University of Agriculture (Poland), Research and Development Project Manager at the University of Economics and Innovation in Lublin (Poland), and Electrical Energy Markets from the Faculty of Electrical Engineering, Automatics, Computer Science and Biomedical Engineering at the AGH University of Science and Technology in Krakow (Poland). Currently Dr. Miros?aw Kwiatkowski is working an assistant professor at the AGH University of Science and Technology, at the Faculty of Energy and Fuels. His published work includes more than 45 papers in reputable international journals and 80 conference proceedings. He is the editor in chief of The International Journal of System Modeling and Simulation (United Arab Emirates), an associate editor of Micro & Nano Letters Journal (United Kingdom) and a member of the many editorial board of internationals journals as well as a member of the organizing and scientific committees many international conferences in Europe, Asia and United States of America. Dr. Miros?aw Kwiatkowski is also a regular reviewer in a most reputable scientific journal.
The paper presents the results of the research on the application of the LBET numerical method with the fast multivariant identification procedure as a tool for analysing the adsorption in NaY zeolites structures on the basis of the carbon dioxide isotherms. The obtained results show that the LBET method give good insight into the adsorption mechanisms as well as the LBET models may be well fitted to data in a wide pressure range, providing accurate evaluation of the monolayer adsorption capacity. The models give also information on adsorbate clusterisation mechanisms, and surface energy distribution.
José R. Ochoa-Gómez
Tecnalia R&I, Spain
Catalystscreening to produceisosorbide bis(methyl carbonate), a green monomer for non-isocyanate pol
José R. Ochoa-Gómez (PhD, MBA)is a Principal Researcher in Tecnalia R&I, the largest Private Spanish Technology Center. He has developed his career combining applied research in Chemical Technology, both in the Industry (CEPSA, ERT-Ercros) and Technology Centers (Leia, Tecnalia), with technology consulting and university teaching (Universities Carlos III and Alfonso X of Madrid). From 2005 to 2009 he was a member of the Chemical Observatory ofthe Spanish Ministry of Industry, Tourism and Commerce. He is the author of 79 articles, 4 book chapters and 1 book, and inventor of 28 patents. He has supervised 6 Doctoral Theses.
Polycarbonates (PCs) of glucose-derived isosorbide (ISO) are currently obtained by melt polycondensation of either ISO with diphenyl carbonate1or ISO-bis(phenyl carbonate) with polyols.2Theseroutes have strong drawbacks such as the high reaction temperature (240 ºC) and the phenol formation which must be recovered for economic feasibility. We have shown that the synthesis of isosorbide PCs is also possible by melt polycondensation of isosorbide bis(methyl carbonate) (IBMC), a barely explored green chemical, and 1,4-butanediol (see Scheme).3Likewise, the IBMC double methoxycarbonyl functionality allows its use in manufacturing non-isocyanate polyurethanes by reaction with diamines (See Scheme).
We have developed a process to obtain IBMC in 99% yield by transesterification of ISO with dimethyl carbonate (DMC),4 using K2CO3 or Cs2CO3 as catalysts (see Scheme). However,most of ISO currently available contains acidic impurities which deactivatethose catalysts so that amounts much higher than the catalytic ones are needed. This presentation reports the results of a study searching for catalysts to overcome this problem. Both basic and mixed acid-base catalysts have been studied. Best results are provided by catalysts having a dual strong-basic/nucleophilic character.
Low Polydispersities from a Novel Free Radical Initiator
Yao Zhang is major in inorganic chemistry as a bachelor in Jilin University, China, and obtained hisdoctoral degree incondensed matter physics from Kyoto University, Japan. Yao focused on the field of itinerant electron magnetism,and suggested spin fluctuations may play a key role in universally explaining the magnetism of weakly itiernat-electron ferromagnets. Currently, Yao is working at Department of Chemistry, Shanghai Jiao Tong university. His work designed on inorganic porous materials is proved to be functional as a radical indicator. Yao thanks the committee for originating the conference, and appreciate your opinions.
Polymers are one of the most important materials in modern society due to the multiple applications in the field of optical, electronic, biomedical areasetc.1 Billion dollars’ worth of polymer have been produced every year, among which half of the production are based on radical method2. Precise synthesis of polymers of designed molecular weight with low polydispersity is crucial for their properties. The most delicate examples with low polydispersity are the natural ones, such as enzymes and nucleic acids. Traditionally, low-polydispersitypolymerswere synthesized through anionic polymerization, reversible addition-fragmentation chain-transfer polymerization, or Atom Transfer Radical method.3-6 Here, we would like to represent a novel version of free radical initiator, which is based on porous materials. The indicator is completely inorganic and relatively green, the progress is believed to be neat and convenient, and its high activity suggests broad applicability. Besides, the indicator is at low cost.At present, apolydispersity (1.06) of polymethylmethacrylate has been observed.
Karpov Phys-Chem Inst., Moscow, Russia, Russia
Kinetic Description of Partially Reversible Catalytic Processes in the Context of the Oscillation Th
Victor Ostrovskii obtained university-level and doctorate education in physchemistry and engineering at Moscow State University of Fine Chemical Technologies (1952-1957), Karpov Phys-Chem. Institute, and took several courses in Lomonosov Moscow State University; was scientific worker and senior staff scientist in Laboratory of Chemical Kinetics and, later, Chief of Sector of Thermodynamics and Calorimetry, Moscow KarpovPhys-Chem. Institute and lecturer in several Russian Universities, is author of ~200 experimental, theoretical, and technical published works in thermodynamics, kinetics, and mechanisms of solid-gas reactions and reactions at solid-gas boundaries and principal (with Dr. Elena Kadyshevich) or personal author of Oscillation theory of catalysis (OTCAT), Theory of kinetics of catalysis near the equilibrium, Life origination hydrate theory (LOH-Theory), Mitosis and replication hydrate theory (MRH-Theory), PFO-CFO Theory of Solar System formation and transformation, Theory of aging, optimal nutrition and life prolongation, and Theory of monochirality origination and racemization delay causes (all are at ResearchGate site).
It was shown by S. Weller  that the procedure of the kinetic description of partially reversible catalytic processes proposed earlier by J. Horiuty didn’t wear well. The theoretically substantiated method for description the kinetics of partially reversible catalytic processes was developed by us on the basis of the Oscillation Theory of Heterogeneous Catalysis [3, 4] and will be presented at this lecture by the examples of industrially significant catalytic processes. As was shown by Weller, the use of the procedure proposed by Horiuty leads to different kinetics depending on the set of the stoichiometric coefficients applied for the notation of the stoichiometric equations of gross reactions. Meanwhile, it is obvious that the kinetics of a reaction by no means depends on the mode of notation ofits stoichiometric equation.Our procedure is logically substantiated and hasn’t this defect. It is grounded on the introduction of the notion of the matching coefficient (MC). The MCs are of the stoichiometric nature; they mutually coordinate stoichiometric equations for chemical reactions similarly to the stoichiometric coefficients which mutually coordinate molar amounts of source substances and products participating in a chemical reaction.The procedure under consideration is proved bya number of reactions.
Adeel Abdulkarim Altuhaish
Growth and Development of Six Wheat (TriticumaestivumL.) Genotypes at Two Different Altitudes under Putrescine Application
Adeelaltuhaish has expertise in plant physiology. His focusing in biochemical and physiological changes in plant particularly crops under abiotic stress condition such as heat and drought stress. His approach to increasing the adaptability of introduced wheat genotypes combined with application of plant growth promoting substances, such as polyamine, to obtain potential wheat genotypes that could be used to develop new adapted wheat varieties to tropical and subtropical regions.
Wheat grown in tropical regions is facing high temperature stress, which is the one of the major limiting factors for growth and development. The objective of the research was to study growth and development of the introduced wheat genotypes under putrescine application at two different altitudes of tropical agro-ecosystem.Field experiments were carried out at mid(600 m asl) and high(1100m asl) altitudes using randomized complete block design with three factors, which were(1) putrescine treatment (0, 1.25 and 2.5 mM),(2) six wheat genotypes and (3) two different altitudes, i.e:high and mid altitudes. Putrescine was sprayed on the aerial parts of plant one week before heading and one week after anthesis stage. Morpho -physiological traits were observed and analyzed.
finding:Thegrowth traitswere affected by temperature increase at mid altitude but putrescine induced significant increments in plant growth at both altitudes except for plant height at mid altitude. Putrescine application increased leaf photosynthesis and decreased intercellular CO2concentration. At mid altitude, high temperature increased flag leaf temperature, MDA content and decreased SOD activity.Putrescine could decrease flag leaf temperature and increased SOD activity.
The sugar was affected by altitude and genotypes.Putrescine was able to improve growth and adaptability of wheat grown in tropical agro-ecosystem.
Hashemite University, Jordan
Increase in atrial fibrillation risk susceptibility due to rs2236609 polymorphism in KCNE1 gene
Foad Alzoughool has expertise in Cellular and Molecular Medicine, My research is directed towards understanding the genetic causes and physiology of cardiac heart rhythm disorders, and others diseases such as breast cancer and rheumatoid arthritis through use of human genetic studies, bioinformatics, cellular electrophysiology and mouse models. We use genome sequencing in families or case cohorts identified through jordanian hospitals, standard bioinfomatic techniques, cloning and site-directed mutagenesis, in vitro clamp recordings to study disease physiology
Background: The genetic variations in potassium voltage-gated channel subfamily E regulatory subunit 1 (KCNE1) gene are reported to contribute in ECG trait distributions and associated with susceptibility to arrhythmias. RS2236609 SNP is reported to significant association with the decrease in P wave and PR interval of ECG that is a predictor of incident atrial fibrillation, the most common sustained cardiac arrhythmia. This study aims to investigate the frequency and the possible association between rs2236609 SNP and AF risk.
Methods: The present study was a case-control study recruit 100 patients suffering from Atrial Fibrillation (AF) with mean age (47 +/- 20 years) and 95 healthy control with age above 55 years with no history of cardiovascular disease, hypertension, or diabetes. Genomic DNA was extracted from whole peripheral blood, and the desired fragment was amplified using polymerase chain reaction followed by restriction digestion with NspI restriction enzyme.
Results: The results showed a significant difference between the SNP variations among AF patients compared to control (P< 0.022). GG genotypes are significantly decreased (OR 0.42, 95% Cl 0.23- 0.79) while GA is significantly increased (OR 2.12, 95% Cl 1.11-4.06), while the AA genotype was not significantly increased (OR2.28 , 95% Cl 0.57- 9.1__) as likely compared to the controls.
Conclusion: Our result showed a significant increased in AF risk in people carrying GG or GA genotype.
University of south florida, USA
Impedance Characterization of Electric Field Mediated Tissue for Cancer Therapy Applications
Richard Gilbert is currently a Professor of Chemical and Biomedical Engineering and the Director of the Center for Molecular Delivery at the University of South Florida. He is a Fellow of the American Institute for Medical and Biological Engineering and an Emeritus Member of the American Association for Cancer Research. He is a former Chair of the Chemical Department in the College of Engineering and a former Professor of Research in the Department of Surgery in the College of Medicine at the University of South Florida. Professor Gilbert holds over 25 U.S. Patents related to electric field mediated drug and gene delivery technology and protocols. His publications include being a special issue co-guest editor on Bioelectrics, (Volume 103, Bioelectrochemistry, ISSN 1567-5394) and a co-editor of "Electrochemotherapy, Ectrogenetherapy, and Transdermal Drug Delivery" (Humana Press, ISBN 0-89603-606-5).
Clinically successful FDA approved trails in the United States of electric field mediated tissue to enhance drug and gene delivery for cancer treatment protocols have emphasized the importance of characterizing the tissue alteration for optimal mass transport of the applicable treatment drug or gene. Since these cancer treatment protocols only require a brief patient interaction and minimally invasive procedures, immediate feedback of favorable tissue conditioning because of the optimally applied electric field forcing function represents a significant improvement to the overall process. Impedance spectroscopy represents one tool to evaluate the tissue's response to the applied field.1 This presentation will review results that demonstrate the usefulness of impedance measurements to predict successful gene delivery through the target tissue and subsequent cell protein production in the targeted tumor cells. The presentation will focus on the development, at the University of South Florida's College of Engineering, of this electric field mediated drug and gene delivery technique. 2 The presentation will indicate tissue impedance alternation as it relates to the relevant chemistry, electrochemistry, electrogenetherapy, as well as chemical and medical engineering principles.
Saif Al Ghafri
University of Western Australia, Australia
High Pressure Thermophysical Properties of Complex Mixtures Relevant to Liquefied Natural Gas (LNG) Processing
Dr Saif Al Ghafri is a postdoctoral research fellow at UWA working in the Thermophysical properties measurements. He obtained his PhD in 2013 on Carbon Capture and Storage (CCS) from Imperial College London, focusing on measurements of the Thermophysical properties of mixtures of carbon dioxide with reservoir fluids. Dr Al Ghafri worked as a postdoctoral research associate at Imperial College for two years before joining UWA. He is currently involved in different LNG projects within the Fluid Science and Resources (FSR) group including vapor-liquid equilibrium, viscosity, solid-liquid equilibrium, density, bubble points and boil-off gas measurements.
Knowledge of the thermophysical properties of complex mixtures at extreme conditions have always been essential to the Liquefied Natural Gas (LNG) industry’s evolution because of the tremendous technical challenges present at all stages in the supply chain from production to liquefaction to transport. In this work, we present a wide range of experimental measurements made for different binary and ternary mixtures relevant to LNG processing. For this purpose, customized and specialized apparatus were designed and validated over the temperature range (200 to 423) K at pressures to 35 MPa. The mixtures studied were (CH4 + C3H8), (CH4 + C3H8 + CO2) and (CH4 + C3H8 + C7H16); in the last of these the heptane contents was up to 10 mol %. Viscosity was measured using a vibrating wire apparatus, while mixture densities were obtained by means of a high-pressure magnetic-suspension densimeter and an isochoric cell apparatus. Surface tensions was measured using the capillary rise method in a visual cell, which also enabled the location of the mixture critical point to be determined from observations of critical opalescence. Mixture heat capacities were measured using a customized high-pressure differential scanning calorimeter (DSC). The extensive experimental data gathered in this work were compared with a variety of different advanced engineering models frequently used for predicting thermophysical properties of mixtures relevant to LNG processing. In many cases the discrepancies between the predictions of different engineering models for these mixtures was large, and the high quality data allowed erroneous but often widely-used models to be identified. The data enable the development of new or improved models, to be implemented in process simulation software, so that the fluid properties needed for equipment and process design can be predicted reliably which is essential for oil and gas industry. This in turn will enable reduced capital and operational expenditure by the LNG industry.
Université Libre de Bruxelles, Belgium, Belgium
Where does Matter come from and why does it obey to Quantum Mechanics?
Mathematician from the Université Libre de Bruxelles ULB (1977). PhD at the University of Lille I (France). Researcher at IRIDIA (ULB, Brussels). Works in the interdisciplinary field, at the intersection of math, physics, chemistry, biology, psychology and (neoplatonist) theology/metaphysics (fundamental science).
We explain briefly, in the first part of the presentation, that the Digital Mechanist Hypothesis in the Cognitive Science, aka Computationalism, enforces the need to derive the conceptual origin of Matter, as stable appearances, in a so much constrained way that such an explanation becomes empirically testable. In the second part of the presentation, we sketch accordingly the mathematical derivation of the laws of physics obtained. We get some quantum logic for the logic of the observable of the universal (Church, Turing) machine, confirming that Mechanism is a plausible principle. We will illustrate also that the logic of digital machine self-reference explains in that setting why the logic of quanta is naturally extended into a logic of qualia, which appears as non sharable private information, common to all digital machine having a precise threshold of logical complexity. This means that in the fundamental domain, we might need to revisit the Aristotelian/Plato controversy on the nature of what can be the fundamental science and reality. Matter and physical laws might thus have a non material, yet mathematical (even arithmetical) explanation, in terms of statistics of internal relative appearances. The quantum appears to be the digital “seen from inside”. A quantum orbital appears to be a relative map on accessible computational continuation in arithmetic. Keyword: Universal Turing machine, Church-Turing thesis, computationalism, digital, Quantum Logic, Orbital, Matter, Observable.